1/22/2024 0 Comments Pneumonia vaccine after effects![]() First hospitalized LRTI was identified using pneumonia codes and acute bronchitis codes. Main Outcomes and Measures First hospitalized all-cause pneumonia was identified in the EMR using primary/secondary discharge diagnosis International Classification of Diseases, Ninth Revision and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes. Individuals were considered vaccinated 14 days following immunization. Data analysis took place from July 2018 to December 2021, and data collection took place from November 2016 to June 2018.Įxposures PCV13 vaccination status was ascertained from the electronic medical record (EMR). The study took place at an integrated health care system with an annual membership more than 4 million individuals, approximately 15% of whom are 65 years or older and broadly representative of the region. Objective To estimate the association between the incidence of hospitalized all-cause pneumonia and lower respiratory tract infections (LRTI) and PCV13 vaccination among older adults at Kaiser Permanente Northern California (KPNC).ĭesign, Setting, and Participants This retrospective cohort study included adults at KPNC aged 65 years or older between July 1, 2015, and June 30, 2018, born after 1936 with no known history of PPV23 or PCV13 receipt before age 65. In 2014, the Advisory Committee for Immunization Practices recommended routine use of PCV13 among adults aged 65 years or older previously only 23-valent pneumococcal polysaccharide vaccine (PPV23) was recommended. Importance Following routine use of 13-valent pneumococcal conjugate vaccine (PCV13) in children in 2010, invasive pneumococcal disease rates have decreased substantially in children and adults. ![]() Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.Association Between PCV13 Vaccination and Hospitalized Pneumonia and Lower Respiratory Tract Infections (LRTI) in Adults ≥65 Years Old, Kaiser Permanente Northern California, July 1, 2014, to June 30, 2018 Adjusted Risk Ratios (RR) of Hospitalized Lower Respiratory Tract Infections (LRTI) in Adults ≥65 Years Old at Kaiser Permanente Northern CaliforniaĮTable 7. Adjusted Risk Ratios (RR) of Hospitalized Pneumonia in Adults ≥65 Years Old at Kaiser Permanente Northern CaliforniaĮTable 6. Unadjusted Incidence Rate (IR) Per 100 000 Person-Years (PY) of Hospitalized Pneumonia and Lower Respiratory Tract Infections (LRTI) in High Risk Adults ≥65 Years Old Born After 1936 by PCV13 Vaccination Status, Kaiser Permanente Northern California, July 1, 2014, to June 30, 2018ĮTable 5. ![]() Unadjusted Incidence Rate Per 100 000 Person-Years of Hospitalized Pneumonia and Lower Respiratory Tract Infections in Adults Born Before 1936 (77 Years or Older) by PCV13 Vaccination Status, Kaiser Permanente Northern California, July 1, 2014, to June 30, 2018ĮTable 4. Unadjusted Incidence Rate Per 100 000 Person-Years of Hospitalized Pneumonia and Lower Respiratory Tract Infections in Study Population of Adults 65 Years or Older by PCV13 Vaccination Status, Kaiser Permanente Northern California, July 1, 2014, to June 30, 2018ĮTable 3. ICD-9 and ICD-10 Codes Used to Identify Increased Risk of Pneumococcal DiseaseĮTable 2.
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